Signs of damage that drive protein degradation

Nature, Published online: 29 January 2025; doi:10.1038/d41586-025-00082-7Many environmental toxins damage proteins, which then must be removed to avoid dangerous protein aggregation and disease. How cells dispose of chemically modified proteins has been unclear, but a discovery offers some clues.

Jan 29, 2025 - 23:59
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Signs of damage that drive protein degradation

Nature, Published online: 29 January 2025; doi:10.1038/d41586-025-00082-7Many environmental toxins damage proteins, which then must be removed to avoid dangerous protein aggregation and disease. How cells dispose of chemically modified proteins has been unclear, but a discovery offers some clues.