H-bonded organic frameworks as ultrasound-programmable delivery platform
Nature, Published online: 05 February 2025; doi:10.1038/s41586-024-08401-0The concept of using hydrogen-bonded organic frameworks triggered by non-invasive focused ultrasound for programmable drug activation is explored and demonstrated practically with the designer drug clozapine N-oxide for deep brain stimulation in mice and rats.
Nature, Published online: 05 February 2025; doi:10.1038/s41586-024-08401-0The concept of using hydrogen-bonded organic frameworks triggered by non-invasive focused ultrasound for programmable drug activation is explored and demonstrated practically with the designer drug clozapine N-oxide for deep brain stimulation in mice and rats.
